Improved detection of bacterial central nervous system infections by use of a broad-range PCR assay.

نویسندگان

  • T Meyer
  • G Franke
  • S K A Polywka
  • M Lütgehetmann
  • J Gbadamosi
  • T Magnus
  • M Aepfelbacher
چکیده

A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid (CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 52 5  شماره 

صفحات  -

تاریخ انتشار 2014